{"id":2828,"date":"2018-10-17T23:30:17","date_gmt":"2018-10-17T13:30:17","guid":{"rendered":"https:\/\/wimr.org.au\/?post_type=wimr_news&#038;p=2828"},"modified":"2024-09-30T18:26:40","modified_gmt":"2024-09-30T08:26:40","slug":"understanding-the-enemy","status":"publish","type":"news","link":"https:\/\/wimr.org.au\/news\/understanding-the-enemy\/","title":{"rendered":"Understanding the enemy"},"content":{"rendered":"<p class=\"lead\">Bethany Horsburgh, a PhD student from the Westmead Institute and University of Sydney, won the Alan Brotherton Prize for her abstract at the 2018 Australasian HIV &amp; AIDS Conference.<\/p>\n<p>Bethany presented her work on using full-length sequencing to understand the genetic traits of latent reservoirs, which contain HIV that is capable of replicating after treatment has ceased.<\/p>\n<figure class=\"caption\">\n<p><figure style=\"width: 300px\" class=\"wp-caption alignleft\"><img fetchpriority=\"high\" decoding=\"async\" src=\"\/wp-content\/uploads\/2024\/09\/Bethany-Horsburgh-Alan-Brotherton-prize_crop.jpg\" alt=\"\" width=\"300\" height=\"296\" \/><figcaption class=\"wp-caption-text\">Bethany (right), with supervisor Associate Professor Sarah Palmer (left).<\/figcaption><\/figure><\/figure>\n<p>\u201cOnly a small portion of HIV is genetically intact and can replicate,\u201d Bethany explained<\/p>\n<p>\u201cThis portion usually \u2018hides\u2019 within the body to avoid being eliminated by treatment. When treatment stops, the virus hidden in latent reservoirs can replicate, and re-infect patients.<\/p>\n<p>\u201cWe were looking for information about what remains in the body during long-term therapy which could help us better target the reservoir.<\/p>\n<blockquote class=\"quote\"><p>\u201cBy understanding certain traits, such as how the reservoir is being maintained, which cells it is in, and what the HIV itself looks like, we have a better understanding of the enemy, and therefore can develop better strategies for cure.\u201d<\/p><\/blockquote>\n<p>&nbsp;<\/p>\n<p>The Alan Brotherton Prize is named after one of Australia\u2019s pioneer HIV activists, who was a key advocate and figure in shaping Australia\u2019s response to the HIV epidemic. The Prize recognises the most outstanding abstract relating to an HIV cure.<\/p>\n<p>Bethany is the second-ever recipient of the award.<\/p>\n<p>\u201cFor me, being awarded a prize in the name of someone who has such an incredible legacy is a huge honour,\u201d Bethany said.<\/p>\n<p>\u201cThe community are key to all we do, and to be recognised in this way is a very humbling experience.\u201d<\/p>\n<p>Congratulations, Bethany!<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Bethany Horsburgh, a PhD student from the Westmead Institute and University of Sydney, won the Alan Brotherton Prize for her abstract at the 2018 Australasian HIV &amp; AIDS Conference. Bethany presented her work on using full-length sequencing to understand the genetic traits of latent reservoirs, which contain HIV that is capable of replicating after treatment [&hellip;]<\/p>\n","protected":false},"featured_media":2829,"parent":0,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"categories":[19],"class_list":["post-2828","news","type-news","status-publish","has-post-thumbnail","hentry","category-cat-news"],"acf":[],"_links":{"self":[{"href":"https:\/\/wimr.org.au\/wp-json\/wp\/v2\/news\/2828","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/wimr.org.au\/wp-json\/wp\/v2\/news"}],"about":[{"href":"https:\/\/wimr.org.au\/wp-json\/wp\/v2\/types\/news"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/wimr.org.au\/wp-json\/wp\/v2\/media\/2829"}],"wp:attachment":[{"href":"https:\/\/wimr.org.au\/wp-json\/wp\/v2\/media?parent=2828"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/wimr.org.au\/wp-json\/wp\/v2\/categories?post=2828"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}