{"id":10556,"date":"2025-02-12T06:59:16","date_gmt":"2025-02-11T20:59:16","guid":{"rendered":"https:\/\/wimr.org.au\/?post_type=impact&#038;p=10556"},"modified":"2025-04-09T11:45:52","modified_gmt":"2025-04-09T01:45:52","slug":"maddie-has-hope-from-wimr-research","status":"publish","type":"impact","link":"https:\/\/wimr.org.au\/impact\/maddie-has-hope-from-wimr-research\/","title":{"rendered":"Maddie has hope from WIMR research"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"10556\" class=\"elementor elementor-10556\" data-elementor-post-type=\"impact\">\n\t\t\t\t<div class=\"elementor-element elementor-element-419dd996 cp-heroyellow e-flex e-con-boxed e-con e-parent\" data-id=\"419dd996\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;gradient&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-390e31a7 e-con-full e-flex e-con e-child\" data-id=\"390e31a7\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7dc3d13 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"7dc3d13\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">Maddie has hope from WIMR research<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-486f9c74 elementor-widget-tablet__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"486f9c74\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u201cThe more people donate and contribute to support this work, the more it gives people like me\u2014and others living with this condition\u2014hope.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-28110688 e-con-full e-flex e-con e-child\" data-id=\"28110688\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-362693d7 elementor-hidden-desktop elementor-hidden-tablet elementor-hidden-mobile elementor-widget elementor-widget-html\" data-id=\"362693d7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<style>\r\n.cp-heroyellow {\r\nbackground: rgb(246,236,207);\r\nbackground: linear-gradient(105deg, rgba(246,236,207,1) 0%, rgba(255,194,14,1) 22%, rgba(249,157,28,1) 100%);\r\n<\/style>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e27dcf2 e-flex e-con-boxed e-con e-parent\" data-id=\"e27dcf2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-63845ff e-con-full e-flex e-con e-child\" data-id=\"63845ff\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-1d53380 e-con-full e-flex e-con e-child\" data-id=\"1d53380\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-0ca3ece e-con-full e-flex e-con e-child\" data-id=\"0ca3ece\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-6b39c6f elementor-widget elementor-widget-text-editor\" data-id=\"6b39c6f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>At just 14 years old, Madeleine is navigating life with ulcerative colitis, a chronic condition that affects her daily life in ways many of her peers never have to think about.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7209be2 e-con-full e-flex e-con e-child\" data-id=\"7209be2\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e8fe3b1 elementor-widget elementor-widget-text-editor\" data-id=\"e8fe3b1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Diagnosed at age 11, Maddie has faced challenges that have made her stronger, more resilient, and deeply appreciative of the people working to understand and treat her condition.<\/p><p>\u201cThere are so many obstacles to overcome just to live life as normally as possible,\u201d Maddie says. \u201cEven things that other 14-year-olds take for granted can be really difficult for me. But I try to focus on the positives\u2014like being part of something bigger, like today, sharing my story.\u201d<\/p><p>Maddie and her family find comfort in knowing that researchers at The Westmead Institute for Medical Research (WIMR) are dedicated to uncovering better treatments\u2014and one day, maybe even a cure\u2014for ulcerative colitis and Crohn\u2019s disease. Led by Professor Andrew Harman and Dr. Kirstie Bertram, the research at WIMR is focused on understanding how the immune system contributes to these conditions and why some people develop severe, lifelong symptoms.<\/p><p>Professor Harman\u2019s team has discovered that a key immune cell is missing in people with Crohn\u2019s disease, which may play a major role in how the disease develops. Their work is now focused on understanding whether this missing cell can be restored, either through new medications or by identifying signals that help it function properly. Thanks to a $1.5 million research grant, WIMR scientists are now studying younger patients with more severe disease, like Maddie, and comparing them to older patients with milder symptoms to understand why some cases are more aggressive.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-dbc1477 e-con-full e-flex e-con e-child\" data-id=\"dbc1477\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0918fba elementor-widget elementor-widget-text-editor\" data-id=\"0918fba\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u201cIt\u2019s so comforting to know that we\u2019re not alone and that there are scientists and researchers dedicated to making a difference.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aab1e90 elementor-widget elementor-widget-heading\" data-id=\"aab1e90\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">For Maddie\u2019s father, this research provides hope<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-da3e744 elementor-widget elementor-widget-text-editor\" data-id=\"da3e744\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><em>\u201cRight now, there\u2019s no prevention for ulcerative colitis\u2014it\u2019s all about treatment,\u201d<\/em> he says. <em>\u201cKnowing that there are teams like the one at WIMR working towards prevention and better treatments gives us confidence. That\u2019s the end goal.\u201d<\/em><\/p><p>While Maddie\u2019s condition isn\u2019t cured, she finds hope in the science happening at WIMR. <em>\u201cIt\u2019s comforting to know that we\u2019re not alone and that researchers are working so hard to help people like me,\u201d<\/em> she says. <em>\u201cIt makes us feel valued, understood, and reassured knowing there are people out there who truly care and want to help.\u201d<\/em><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-b7b8f8c e-con-full sticky_sec e-flex e-con e-child\" data-id=\"b7b8f8c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9c6ae3b elementor-widget elementor-widget-sidebar\" data-id=\"9c6ae3b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"sidebar.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div 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support this work, the more it gives people like me\u2014and others living with this condition\u2014hope.\u201d At just 14 years old, Madeleine is navigating life with ulcerative colitis, a chronic condition that affects her daily life in ways many of her peers never [&hellip;]<\/p>\n","protected":false},"featured_media":10565,"menu_order":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"no-sidebar","site-content-layout":"","ast-site-content-layout":"full-width-container","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"disabled","ast-breadcrumbs-content":"","ast-featured-img":"disabled","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"default","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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